Latest in FPIES Research & Publications
Food Protein-Induced Enterocolitis Syndrome: An Update on Natural History and Review of Management Leonard, S.; Nowak-Wegrzyn A. Food Protein-Induced Enterocolitis Syndrome: An Update on Natural |
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Current Understanding of the Immune Mechanisms of FPIES. Expert Review This is the most up to date article on FPIES immune mechanisms. Doctors at the Jaffe Food Allergy Institute at the Mt. Sinai School of Medicine recognize that FPIES is an under recognized and frequently misdiagnosed allergy, and outline the current understandings and future potential of FPIES research. Caubet, J.;Nowak-Wegrzyn, A. Current Understanding of the Immune Mechanisms of FPIES. Expert |
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A full review of the latest guidelines for food allergy. See section 4.3.2 for FPIES information. NIAID-Sponsored Expert panel.Guidelines for the Diagnosis and Management of Food Allergy in the |
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Understanding Non-IgE Mediated GI Disorders |
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Nomura, I. et al. Four distinct subtypes of non-IgE-mediated gastrointestinal food allergies in neonates and |
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Food Protein-Induced Proctitis/Colitis, Enteropathy, and Enterocolitis of Infancy This article defines the differential diagnosis for symptoms that present in infancy. Abstract available only. Available for purchase through qualifying UpToDate membership. Lake, A. Food Protein-Induced Proctitis/Colitis, Enteropathy, and Enterocolitis of Infancy. UpToDate, January 2011, Retrieved from: http://www.uptodate.com/contents/food-protein-induced-proctitis-colitis-enteropathy-and-enterocolitis-of-infancy . |
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An annually updated, comprehensive protein intolerance overview including differentials for diagnosis. Nocerino, A.; Guandalini, S. Protein Intolerance. Retrieved from: http://emedicine.medscape.com/article/931548-overview. |
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Food Allergy: Review, Classification and Diagnosis Written in 2009 by Children's Hospital of Philadelphia medical doctors, this article describes IgE allergy, oral tolerance and Non-IgE allergy in the context of rising food allergy diagnosis and treatments. Includes an excellent graph to illustrate IgE, Non-IgE and intolerances. Cianferoni, A.; Spergel, J.M. Food Allergy: Review, Classification and Diagnosis. Allergology |
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Written by a doctor researching protein intolerances in many populations, this article contains in depth discussion of the involvement of the GI tract in non-IgE mediated allergies. This article recognizes the necessity of early recognition and treatment for the management of both non-IgE allergies and FPIES specifically. Jyonouchi, H. Non-IgE Food Allergy. Inflammation & Allergy. Drug Target. 2008; 7(3): 1-7. |
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Nonimmunoglobin E-Mediated Immune Reactions to Foods This article, published in 2006, written by a doctor at Children’s Hospital of Philadelphia, recognizes the increase in Non-IgE food allergy. Includes a table for differential diagnosis within Non-IgE allergy. Spergel, J. Nonimmunoglobin E-Mediated Immune Reactions to Foods. Allergy, Asthma & Clinical Immunology, 2006; 2 (2): 78-85. |
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Further FPIES Studies, Research, and Publications |
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Rice: A Common and Severe Cause of Food Protein-Induced Enterocolitis Syndrome This Australian based study, written in 2009, defines rice FPIES and milk/soy FPIES, as well as the differences and similarities in presentation. Mehr, S.; Kakakios, A.; Kemp A. Rice: A Common and Severe Cause of Food Protein-Induced Enterocolitis Syndrome. Pediatrics November 2009; 124 (Supplement 2): S126 -S127. |
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Food Protein-Induced Enterocolitis Syndrome Written in 2009, this is a follow up to the 2003 study by doctors at the Jaffe Food Allergy Institute at Mt. Sinai School of Medicine. Nowak-Wegrzyn, A.; Muraro, A. Food Protein-Induced Enterocolitis Syndrome. Current Opinion Allergy Clinical Immunology. August 2009;9(4):371-7. |
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Food Protein-Induced Enterocolitis Syndrome: A Review. Written in 2009, this article provides a brief and informative review of the current knowledge of FPIES. There is a table provided for comparisons of FPIES, Gastroenteritis and IgE allergies, and discussions for the differential diagnosis and management of FPIES. van der Poel L.A.; Fox A.; Du Toit G. Food Protein-Induced Enterocolitis Syndrome: A Review. Current Allergy & Clinical Immunology, June 2009; 22 (2): 56-57. |
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Food Protein-Induced Enterocolitis Syndrome: Case Presentations and Management Lessons Written by doctors at the Jaffe Food Allergy Institute at Mt. Sinai School of Medicine. Sicherer, S. Food Protein-Induced Enterocolitis Syndrome: Case Presentations and Management Lessons. The Journal of Allergy and Clinical Immunology. January 2005; 115 (1): 149-156. |
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Food Protein-Induced Enterocolitis Syndrome Caused by Solid Food Proteins Written in 2003 by doctors at the Jaffe Food Allergy Institute at Mount Sinai School of Medicine, this articles includes case studies of FPIES. This was one of the first studies to outline FPIES by solid foods, as well as the increasing prevalence of this disorder. Nowak-Wegrzyn, A.; Sampson, H.A.; Wood, R.A.; Sicherer, S.H. Food Protein-Induced Enterocolitis Syndrome Caused by Solid Food Proteins. PEDIATRICS April 2003; 111 (4): 829-835. |
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Food Protein-Induced Enterocolitis Syndrome: Clinical Perspectives This article reviews the first acknowledgment of FPIES by Dr. Powell in the 1970’s. Powell was the first to recognize that symptoms mimicking FPIES need to be ruled out for diagnosis, and established initial criteria for oral food challenges. The authors delineate the classic clinical features, diagnosis and management of FPIES in relation to clinical syndromes that share features with it (atypical FPIES) and other food-allergic disorders affecting the gut. Written by doctors at the Jaffe Food Allergy Institute at Mt. Sinai School of Medicine. Sicherer, S. Food Protein-Induced Enterocolitis Syndrome: Clinical Perspectives. Journal of Pediatric Gastroenterology & Nutrition: January 2000; 30 (1): S45-S49. |
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Clinical Features of Food Protein Induced Enterocolitis Syndrome This article was written by the doctors at the Jaffe Food Allergy Institute of Mount Sinai School of Medicine, both pioneers in the research on FPIES. It outlines the clinical features that may be identified following studies on infants presenting with FPIES symptoms. Sicherer, S.; Eigenmann, P.; Sampson, H. Clinical Features of Food Protein Induced Enterocolitis |
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Additional FPIES Publications |
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Allergen Patch Test in Children With Food Allergy-related Gastrointestinal Symptoms Visitsunthorn, N.; Boonyaviwat, O.; Pacharn, P.; Piboonpocanun, O.; Vichyanond, P.Allergen Patch Test |
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Atopy Patch Test for the Diagnosis of Food Protein-Induced Enterocolitis Syndrome Fogg MI, Brown-Whitehorn TA, Pawlowski NA, Spergel JM. Atopy Patch Test for the Diagnosis of Food |
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The Mother of All Food Allergy This article was written as a commentary to an article published in the same issue of The Journal of Pediatrics: “A consistent pattern of minor immunodeficiency and subtle enteropathy in children with multiple food allergy,” by a leading gastroenterologist in Eosinophilic disorders. It offers excellent perspective from the medical community, and outlines the course of diagnosis for an FPIES patient. Putnam, P. The Mother of All Food Allergy.The Journal of Pediatrics. July 2003; 143 (1): 7-9. |
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Latcham et al. A Consistent Pattern of Minor Immunodeficiency and Subtle Enteropathy in Children with Multiple Food AllergyThe Journal of Pediatrics 2003; 143:39-47 |
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